CPI-0610
| CAS No. | 1380087-89-7 | Cat. No. | BCP10741 |
| Name | CPI-0610 | ||
| Synonyms | CPI 0610; CPI0610; BET bromodomain inhibitor; | ||
| Formula | C20H16ClN3O2 | M. Wt | 365.81 |
| Description | CPI-0610 is a small molecule inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor CPI-0610 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. | ||
| Pathways | Epigenetics | ||
| Targets | Epigenetic Reader Domain | ||
Structure
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