Tenofovir alafenamide

  • Chemical Properties
CAS No. 379270-37-8 Cat. No. BCP10770
Name Tenofovir alafenamide
Synonyms GS-7340;GS7340;GS 7340;
Formula C21H29N6O5P M. Wt 476.47
  • Biological Activity
Description Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevent HIV from multiplying and can reduce the amount of HIV in the body. Tenofovir alafenamide is a prodrug, which means that it is an inactive drug. In the body, tenofovir alafenamide is converted to tenofovir diphosphate (TFV-DP). Tenofovir alafenamide fumarate was approved in November 2015 for treatment of HIV-1.
Pathways Microbiology/Virology 
Targets Reverse Transcriptase HIV 

Structure

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