Tenofovir alafenamide
CAS No. | 379270-37-8 | Cat. No. | BCP10770 |
Name | Tenofovir alafenamide | ||
Synonyms | GS-7340;GS7340;GS 7340; | ||
Formula | C21H29N6O5P | M. Wt | 476.47 |
Description | Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevent HIV from multiplying and can reduce the amount of HIV in the body. Tenofovir alafenamide is a prodrug, which means that it is an inactive drug. In the body, tenofovir alafenamide is converted to tenofovir diphosphate (TFV-DP). Tenofovir alafenamide fumarate was approved in November 2015 for treatment of HIV-1. | ||
Pathways | Microbiology/Virology | ||
Targets | Reverse Transcriptase HIV |
Structure
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