Tenofovir alafenamide fumarate
| CAS No. | 379270-38-9 | Cat. No. | BCP10778 |
| Name | Tenofovir alafenamide fumarate | ||
| Synonyms | Tenofovir alafenamide;GS-7340 fumarate;GS7340 fumarate;GS 7340 fumarate; | ||
| Formula | C25H33N6O9P | M. Wt | 592.54 |
| Description | Tenofovir alafenamide, also known as TAF and GS-7340, is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevent HIV from multiplying and can reduce the amount of HIV in the body. Tenofovir alafenamide is a prodrug, which means that it is an inactive drug. In the body, tenofovir alafenamide is converted to tenofovir diphosphate (TFV-DP). Tenofovir alafenamide fumarate was approved in November 2015 for treatment of HIV-1. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Reverse Transcriptase HIV | ||
Structure
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