SAR7334
| CAS No. | 1333210-07-3 | Cat. No. | BCP11028 |
| Name | SAR7334 | ||
| Synonyms | SAR-7334; SAR 7334; TRCP6 inhibitor; | ||
| Formula | C21H22ClN3O | M. Wt | 367.87 |
| Description | SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | TRP Channel | ||
Structure
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