JZL-184
| CAS No. | 1101854-58-3 | Cat. No. | BCP28334 |
| Name | JZL-184 | ||
| Synonyms | JZL184; JZL 184; | ||
| Formula | C27H24N2O9 | M. Wt | 520.49 |
| Description | JZL184 is highly selective, and potent MAGL inhibitor ( monoacylglycerol lipase inhibitor). JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome. JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action. JZL184 also suppresses inflammatory pain in the mouse carrageenan model. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | MAGL | ||
Structure
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