Ripasudil hydrochloride dihydrate

  • Chemical Properties
CAS No. 887375-67-9 Cat. No. BCP11082
Name Ripasudil hydrochloride dihydrate
Synonyms K-115 HCl dihydrate; K115 HCl dihydrate; K 155 HCl dihydrate; Ripasudil HCl dihydrate;
Formula C15H23ClFN3O4S M. Wt 395.88
  • Biological Activity
Description K-115, an isoquinolinesulfonamide compound, is a highly selective and potent (IC50 = 31 nM) Rho-kinase inhibitor; is in Phase II clinical development in patients with POAG or ocular hypertension.
Related Products 223645-67-8(Ripasudil) 223644-02-8(Ripasudil Hydrochloride)
Pathways Cell Cycle/DNA Damage TGF beta/Smad  Wnt/Stem Cell 
Targets ROCK 

Structure

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