C75 trans
| CAS No. | 191282-48-1 | Cat. No. | BCP11074 |
| Name | C75 trans | ||
| Synonyms | (±)-C75;C75;C-75;C 75;trans-4-carboxy-5-octyl-3-methylenebutyrolactone; | ||
| Formula | C14H22O4 | M. Wt | 254.32 |
| Description | (±)-C75 is a stable inhibitor of FAS that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.(±)-C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FAS | ||
Structure
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