β-Nicotinamide Mononucleotide

  • Chemical Properties
CAS No. 1094-61-7 Cat. No. BCP11124
Name β-Nicotinamide Mononucleotide
Synonyms Nicotinamide mononucleotide;β-nicotinamide D-ribonucleotide;Beta-Nicotinamide mononucleotide;NMN;β-NM;
Formula C11H15N2O8P M. Wt 334.22
  • Biological Activity
Description β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate.Nicotinamide Mononucleotide, also known as ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). Because NADH is a cofactor for processes inside mitochondria, for sirtuins, and for PARP, NMN has been studied in animal models as a potential neuroprotective and anti-aging agent. Dietary supplement companies have aggressively marketed NMN products claiming those benefits, though there is no clinical study on humans published yet.
Pathways Protease/Metabolic Enzyme 
Targets Nampt 

Structure

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