Dolasetron

  • Chemical Properties
CAS No. 115956-12-2 Cat. No. BCP11430
Name Dolasetron
Synonyms MDL-73147;MDL73147;HSDB 7565; HSDB7565; HSDB-7565; Dolasetronum;
Formula C19H20N2O3 M. Wt 325.38
  • Biological Activity
Description Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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