Amitifadine
| CAS No. | 410074-73-6 | Cat. No. | BCP11481 |
| Name | Amitifadine | ||
| Synonyms | EB-1010;EB 1010;EB1010;DOV 21947;DOV-21947;DOV21947; | ||
| Formula | C11H11Cl2N | M. Wt | 228.12 |
| Description | Amitifadine, also known as DOV-21,947 or EB-1010, is an antidepressant drug candidate. It is a so-called triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). Amitifadine reduces nicotine self-administration in female rats. Amitifadine reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor Dopamine Receptor | ||
Structure
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