Ginsenoside Rd
| CAS No. | 52705-93-8 | Cat. No. | BCP11505 |
| Name | Ginsenoside Rd | ||
| Synonyms | Gypenoside VIII; | ||
| Formula | C48H82O18 | M. Wt | 947.15 |
| Description | Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively. | ||
| Pathways | Ion Channel/Membrane Transporter Protease/Metabolic Enzyme NFκB | ||
| Targets | Calcium Channel Cytochrome P450 NF κB | ||
Structure
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