Fimasartan

  • Chemical Properties
CAS No. 247257-48-3 Cat. No. BCP11616
Name Fimasartan
Synonyms BR-A657; BR A657; BRA657; BRA 657;
Formula C27H31N7OS M. Wt 501.65
  • Biological Activity
Description Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys. Fimasartan was approved for use in South Korea in September 9th, 2010.
Pathways GPCR/G Protein 
Targets Angiotensin Receptor 

Structure

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