MI 2 MALT1 inhibitor
CAS No. | 1047953-91-2 | Cat. No. | BCP11666 |
Name | MI 2 MALT1 inhibitor | ||
Synonyms | MI-2;MI2; | ||
Formula | C19H17Cl3N4O3 | M. Wt | 455.72 |
Description | MI-2 selectively killed ABC-DLBCL cell lines with CD79A/B, CARMA1, and/or MYD88 mutations but not those occurring in proteins downstream of MALT1, including those with A20 homozygous deletion or TAK1 mutation. Both MI-2 and Z-VRPR-FMK reduced nuclear c-REL to a similar extent, without affecting whole-cell levels of this protein. In both cell lines, exposure to MI-2 caused a clear reduction of nuclear c-REL whereas it did not affect p65 levels. | ||
Pathways | NFκB | ||
Targets | MALT1 |
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.