Cefepime hydrochloride hydrate

CAS No.	123171-59-5	Cat. No.	BCP11707
Name	Cefepime hydrochloride hydrate
Synonyms	Cefepime HCl hydrate; Cefepime hydrochloride monohydrate;BMY 28142 HCl.H2O;BMY-28142 HCl.H2O;BMY28142 HCl.H2O;
Formula	C19H25ClN6O5S2.HCl.H2O	M. Wt	571.49

Description	Cefepime Hydrochloride is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.
Pathways	Microbiology/Virology
Targets	Antibiotic

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