Plerixafor octahydrochloride
| CAS No. | 155148-31-5 | Cat. No. | BCP11743 |
| Name | Plerixafor octahydrochloride | ||
| Synonyms | Plerixafor 8HCl;AMD3100 8HCl;JM3100 8HCl;SID791 8HCl;AMD3100; AMD-3100; AMD 3100; JM 3100; JM3100; JM-3100; SDZ-SID-791; | ||
| Formula | C28H62Cl8N8 | M. Wt | 794.47 |
| Description | Plerixafor octahydrochloride is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.Plerixafor, also known as AMD3100, is a bicyclam with hematopoietic stem cell-mobilizing activity. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. | ||
| Related Products | 110078-46-1（Plerixafor ） 155148-32-6（Plerixafor Octahydrobromide） | ||
| Pathways | GPCR/G Protein | ||
| Targets | CXCR | ||
Structure
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