LDE225 HCL
| CAS No. | 1218778-76-7 | Cat. No. | BCP11861 |
| Name | LDE225 HCL | ||
| Synonyms | LDE 225 HCL;LDE-225 HCL;Erismodegib hydrochloride;NVP-LDE225 HCl;Sonidegib hydrochloride; | ||
| Formula | C26H27ClF3N3O3 | M. Wt | 521.97 |
| Description | Sonidegib (Erismodegib, NVP-LDE225,LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Smoothened/Smo | ||
Structure
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