Fosfomycin disodium

  • Chemical Properties
CAS No. 26016-99-9 Cat. No. BCP11834
Name Fosfomycin disodium
Synonyms Fosfomycin Disodium Salt;Disodium phosphonomycin;Fosfomycin sodium;Phosphomycin disodium salt; (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid disodium salt;
Formula C3H5Na2O4P M. Wt 182.02
  • Biological Activity
Description Fosfomycin is a phosphoenolpyruvate analogue and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties. Fosfomycin binds to and inactivates the enzyme enolpyruvate transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis and bacterial cell death.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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