Baclofen

  • Chemical Properties
CAS No. 1134-47-0 Cat. No. BCP11844
Name Baclofen
Synonyms beta-(Aminomethyl)-4-chlorobenzenepropanoic acid; Lioresal;
Formula C10H12ClNO2 M. Wt 213.66
  • Biological Activity
Description Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission.
Pathways Ion Channel/Membrane Transporter 
Targets GABA Receptor 

Structure

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