Triphenylmethyl Irbesartan
| CAS No. | 138402-10-5 | Cat. No. | BCP12008 |
| Name | Triphenylmethyl Irbesartan | ||
| Synonyms | SR-47436; BMS-186295;SR 47436; BMS 186295;SR47436; BMS186295; | ||
| Formula | C44H42N6O | M. Wt | 670.84 |
| Description | Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Angiotensin Receptor | ||
Structure
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