Cephalothin Sodium

  • Chemical Properties
CAS No. 58-71-9 Cat. No. BCP12072
Name Cephalothin Sodium
Synonyms Cefalotin sodium; Sodium cephalothin; Cephalothin sodium salt; Sodium cefalotin;Cephalothin Monosodium Salt;
Formula C16H15N2NaO6S2 M. Wt 418.41
  • Biological Activity
Description Cephalothin Sodium is the sodium salt form of cephalothin, a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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