Oxaprozin

  • Chemical Properties
CAS No. 21256-18-8 Cat. No. BCP28431
Name Oxaprozin
Synonyms Oxaprozinum;DL-8280;DR-3355;Hoe-280;ORF-28489;Ru-43280;Tarivid; Wy21743;
Formula C18H15NO3 M. Wt 293.32
  • Biological Activity
Description Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.
Pathways NFκB 
Targets NF κB 

Structure

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