Cefpodoxime proxetil

  • Chemical Properties
CAS No. 87239-81-4 Cat. No. BCP12056
Name Cefpodoxime proxetil
Synonyms Vantin;Banan; Doxef; CS 807; Cephalosporin 807; CS 807; CS-807; Doxef; U 76252; U-76,252;
Formula C21H27N5O9S2 M. Wt 557.59
  • Biological Activity
Description Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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