Colistin sulfate

  • Chemical Properties
CAS No. 1264-72-8 Cat. No. BCP12103
Name Colistin sulfate
Synonyms Belcomycin Sulfate; Polymixin E; Polymyxin E Sulfate;
Formula 2(C52H98N16O13).5(H2SO4) M. Wt 2801.27
  • Biological Activity
Description Colistin sulfate is a NADH quinone oxidoreductase inhibitor that induces formation of pores in membranes of gram negative bacteria. It is highly neurotoxic and nephrotoxic.Colistin, a polypeptide antibiotic, is bactericidal to gram-negative bacteria by interfering with the structure and function of the outer and cytoplasmic membranes of bacteria.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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