依他普仑
| CAS号 | 128196-01-0 | 货号 | BCP12154 |
| 中文名 | 依他普仑 | ||
| 英文名 | Escitalopram | ||
| 中文别名 | |||
| 英文别名 | (S)-Citalopram; S-(+)-Citalopram;Seroplex; | ||
| 分子式 | C22H23FN2O5 | 分子量 | 414.43 |
| 生物活性 | Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | SSRI | ||
结构式
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