RO4987655
| CAS No. | 874101-00-5 | Cat. No. | BCP12182 |
| Name | RO4987655 | ||
| Synonyms | RO 4987655;RO-4987655;CH-4987655;CH 4987655;CH4987655; | ||
| Formula | C20H19F3IN3O5 | M. Wt | 565.28 |
| Description | MEK inhibitor RO4987655 binds to and inhibits MEK, which may result in the inhibition of MEK-dependent cell signaling and the inhibition of tumor cell proliferation. MEK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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