阿洛司他丁酸
| CAS号 | 76684-89-4 | 货号 | BCP12303 |
| 中文名 | 阿洛司他丁酸 | ||
| 英文名 | Loxistatin acid | ||
| 中文别名 | |||
| 英文别名 | E-64-C;E-64 C;E-64C;E64C;EP 475;EP475;EP-475; | ||
| 分子式 | C15H26N2O5 | 分子量 | 314.38 |
| 生物活性 | Loxistatin Acid, a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.The compound has been demonstrated to form a complex with papain by binding via a thioether covalent bond. Studies indicate that E-64-c, also known as Ep-475, is a more potent inhibitor of cathepsins B and L compared to E-64. Mouse lymphosarcoma LS studies show that Ep-475 decreases the effects of cyclophosphamide. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Cathepsin | ||
结构式
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