(S)-酮咯酸
| CAS号 | 66635-92-5 | 货号 | BCP28452 |
| 中文名 | (S)-酮咯酸 | ||
| 英文名 | (S)-Ketorolac | ||
| 中文别名 | 酮咯酸S-异构体; | ||
| 英文别名 | Ketorolac S-Isomer;(-)-Ketorolac; | ||
| 分子式 | C15H13NO3 | 分子量 | 255.26 |
| 生物活性 | (S)-ketorolac is a 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It has a role as an analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor and a non-steroidal anti-inflammatory drug. It is an enantiomer of a (R)-ketorolac. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | COX | ||
结构式
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