卡前列素氨基丁三醇
| CAS号 | 58551-69-2 | 货号 | BCP28453 |
| 中文名 | 卡前列素氨基丁三醇 | ||
| 英文名 | Carboprost tromethamine | ||
| 中文别名 | 卡前列腺氨丁三醇; | ||
| 英文别名 | |||
| 分子式 | C21H36O5.C4H11NO3 | 分子量 | 489.64 |
| 生物活性 | Carboprost Tromethamine is the tromethamine salt of the (15S)-15 methyl analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha) with oxytocic activity. Mimicking endogenous PGF2 alpha, carboprost activates prostaglandin F receptor, a G-protein coupled receptor, on smooth muscle cells, thereby resulting in smooth muscle contractions. When administered intramuscularly on gravid subjects, this agent induces myometrium contractions, thereby initiating luteolysis and consequently parturition. Furthermore, carboprost's action on vascular smooth muscle and gastrointestinal tract sphincters leads to raised blood pressure and induces vomiting or diarrhea, respectively. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Prostaglandin Receptor | ||
结构式
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