Paroxetine hydrochloride
CAS No. | 78246-49-8 | Cat. No. | BCP28459 |
Name | Paroxetine hydrochloride | ||
Synonyms | Paroxetine Hcl; Paroxat; Aropax 20; BRL29060 hydrochloride; BRL29060A; Paxil; Seroxat; | ||
Formula | C19H21ClFNO3 | M. Wt | 365.83 |
Description | Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression. It is a highly potent and selective ST (serotonin transporter/5-HT) uptake inhibitor. It acts by binding to ST (serotonin transporter/SERT) with high affinity. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter. Paroxetine HCl has also displayed a high affinity for muscarinic acetylcholine receptors. | ||
Pathways | Neuro Signaling Pathway | ||
Targets | SSRI |
Structure
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