Paroxetine hydrochloride

  • Chemical Properties
CAS No. 78246-49-8 Cat. No. BCP28459
Name Paroxetine hydrochloride
Synonyms Paroxetine Hcl; Paroxat; Aropax 20; BRL29060 hydrochloride; BRL29060A; Paxil; Seroxat;
Formula C19H21ClFNO3 M. Wt 365.83
  • Biological Activity
Description Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression. It is a highly potent and selective ST (serotonin transporter/5-HT) uptake inhibitor. It acts by binding to ST (serotonin transporter/SERT) with high affinity. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter. Paroxetine HCl has also displayed a high affinity for muscarinic acetylcholine receptors.
Pathways Neuro Signaling Pathway 
Targets SSRI 

Structure

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