Rosiglitazone sodium

CAS No.	316371-83-2	Cat. No.	BCP28479
Name	Rosiglitazone sodium
Synonyms	BRL49653; BRL-49653; BRL 49653; HSDB 7555; HSDB-7555; HSDB7555; TDZ 01; TDZ-01; TDZ01;
Formula	C18H18N3NaO3S	M. Wt	379.41

Description	Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Rosiglitazone is a member of the thiazolidinedione class of drugs. Thiazolidinediones act as insulin sensitizers. They reduce glucose, fatty acid, and insulin blood concentrations. They work by binding to the peroxisome proliferator-activated receptors (PPARs). PPARs are transcription factors that reside in the nucleus and become activated by ligands such as thiazolidinediones. Thiazolidinediones enter the cell, bind to the nuclear receptors, and alter the expression of genes.
Pathways	Cell Cycle/DNA Damage
Targets	PPAR

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