Azasetron hydrochlorid

  • Chemical Properties
CAS No. 123040-69-7 Cat. No. BCP12756
Name Azasetron hydrochlorid
Synonyms Y-25130 hydrochloride;Y 25130 hydrochloride;Y25130 hydrochloride;
Formula C17H20ClN3O3.HCl M. Wt 386.28
  • Biological Activity
Description Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27. It is used in the management of nausea and vomiting induced by cancer chemotherapy (such as cisplatin chemotherapy). Azasetron hydrochloride is given in a usual dose of 10 mg once daily by mouth or intravenously.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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