Doxepin hydrochloride

CAS No.	1229-29-4	Cat. No.	BCP28507
Name	Doxepin hydrochloride
Synonyms	Doxepin Hydrochloride; Silenor; Adapin; Novoxapin; Aponal; Toruan; Quitaxon; Sinequan; Sinquan; Xepin; Zonalon;
Formula	C19H22ClNO	M. Wt	315.84

Description	Doxepin hydrochloride is a highly potent Histamine H1 Receptor (histamine H1) antagonist. Doxepin hydrochloride also binds to histamine H4 receptor. Doxepin hydrochloride is an inhibitor of AR and mAChR. Doxepin Hydrochloride is a dibenzoxepin derivative and tricyclic antidepressant with antipruritic and sedative activities. Doxepin also has antagonistic effects on histamine (H1 and H2), 5-HT2, alpha-1 adrenergic, and muscarinic receptors. The antipruritic effect of this agent is the result mediated through inhibition of histamine receptors.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Histamine Receptor SSRI

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