盐酸多塞平
| CAS号 | 1229-29-4 | 货号 | BCP28507 |
| 中文名 | 盐酸多塞平 | ||
| 英文名 | Doxepin hydrochloride | ||
| 中文别名 | |||
| 英文别名 | Doxepin Hydrochloride; Silenor; Adapin; Novoxapin; Aponal; Toruan; Quitaxon; Sinequan; Sinquan; Xepin; Zonalon; | ||
| 分子式 | C19H22ClNO | 分子量 | 315.84 |
| 生物活性 | Doxepin hydrochloride is a highly potent Histamine H1 Receptor (histamine H1) antagonist. Doxepin hydrochloride also binds to histamine H4 receptor. Doxepin hydrochloride is an inhibitor of AR and mAChR. Doxepin Hydrochloride is a dibenzoxepin derivative and tricyclic antidepressant with antipruritic and sedative activities. Doxepin also has antagonistic effects on histamine (H1 and H2), 5-HT2, alpha-1 adrenergic, and muscarinic receptors. The antipruritic effect of this agent is the result mediated through inhibition of histamine receptors. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Histamine Receptor SSRI | ||
结构式
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