CH-223191
| CAS No. | 301326-22-7 | Cat. No. | BCP12814 |
| Name | CH-223191 | ||
| Synonyms | CH223191;CH 223191; | ||
| Formula | C19H19N5O | M. Wt | 333.39 |
| Description | in vitro: CH-223191 preferentially inhibits the ability of some classes of AhR agonists (2,3,7,8-tetrachlorodibenzo-p-dioxin and related HAHs), but not others (PAHs, flavonoids, or indirubin), to bind to and/or activate the AhR and AhR signal transduction. CH-223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR . | ||
| Pathways | Others Pathway | ||
| Targets | AhR | ||
Structure
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