Tegaserod

  • Chemical Properties
CAS No. 145158-71-0 Cat. No. BCP12797
Name Tegaserod
Synonyms SDZ-HTF-919; SDZ-HTF919; SDZ-HTF 919; SDZ HTF-919; SDZHTF-919; HTF919; HTF-919; HTF 919;
Formula C16H23N5O M. Wt 301.39
  • Biological Activity
Description Tegaserod is a 5-HT4 agonist for the management of irritable bowel syndrome and constipation. Approved by the FDA in 2002, it was subsequently removed from the market in 2007 due to FDA concerns about possible adverse cardiovascular effects. Before then, it was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating, and constipation associated with irritable bowel syndrome. Its use was also approved to treat chronic idiopathic constipation.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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