O-去甲文拉法辛
| CAS号 | 93413-62-8 | 货号 | BCP28517 |
| 中文名 | O-去甲文拉法辛 | ||
| 英文名 | O-Desmethylvenlafaxine | ||
| 中文别名 | |||
| 英文别名 | Desvenlafaxine; | ||
| 分子式 | C16H25NO2 | 分子量 | 263.38 |
| 生物活性 | Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause. Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. | ||
| 信号通路 | Neuro Signaling Pathway | ||
| 靶 点 | SSRI | ||
结构式
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