Cromolyn sodium

  • Chemical Properties
CAS No. 15826-37-6 Cat. No. BCP12933
Name Cromolyn sodium
Synonyms Disodium Cromoglycate;Gynazole;
Formula C23H14O11.2Na M. Wt 512.33
  • Biological Activity
Description Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. Pretreatment of IIR mice with Cromolyn sodium prior to ischemia exhibited no changes of ET-1 levels, injury score and inflammation (P>0.05, PreCr vs. M groups). In conclusion, administration of Cromolyn sodium after reperfusion, but not prior to ischemia, attenuates IIRI by downregulating ET-1 and suppressing sustained MC activation . cromolyn sodium has a role in the prevention of Chronic lung disease(CLD). Cromolyn sodium cannot be recommended for the prevention of CLD in preterm infants .
Pathways Ion Channel/Membrane Transporter 
Targets Calcium Channel 

Structure

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