KNK437
| CAS No. | 218924-25-5 | Cat. No. | BCP28527 |
| Name | KNK437 | ||
| Synonyms | KNK-437; KNK 437;Heat Shock Protein Inhibitor I; | ||
| Formula | C13H11NO4 | M. Wt | 245.23 |
| Description | KNK437 is a novel inhibitor of acquisition of thermotolerance and heat shock protein. KNK437 inhibit stress-induced synthesis of heat shock proteins (HSPs). KNK437 is an effective radiosensitizer that targets multiple pro-survival stress response pathways. KNK437 is a useful agent for enhancing the efficiency of hyperthermic therapy which has less toxic side-effects in prostate cancer. | ||
| Pathways | Protease/Metabolic Enzyme Cell Cycle/DNA Damage | ||
| Targets | HSP | ||
Structure
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