达卡他韦二盐酸盐
| CAS号 | 1009119-65-6 | 货号 | BCP13025 |
| 中文名 | 达卡他韦二盐酸盐 | ||
| 英文名 | Daclatasvir dihydrochloride | ||
| 中文别名 | |||
| 英文别名 | Daclatasvir 2HCl;BMS-790052 dihydrochloride;BMS790052 dihydrochloride;BMS 790052 dihydrochloride; EBP883; EBP 883; EBP-883; | ||
| 分子式 | C40H52Cl2N8O6 | 分子量 | 811.8 |
| 生物活性 | Daclatasvir is NS5A inhibitor and a drug for the treatment of hepatitis C (HCV). It is was developed by Bristol-Myers Squibb and was approved in Europe on 22 August 2014. Daclatasvir inhibits the HCV nonstructural protein NS5A. Recent research suggests that it targets two steps of the viral replication process, enabling rapid decline of HCV RNA. Daclatasvir has been tested in combination regimens with pegylated interferon and ribavirin, as well as with other direct-acting antiviral agents including asunaprevir and sofosbuvir. | ||
| 信号通路 | Protease/Metabolic Enzyme Microbiology/Virology | ||
| 靶 点 | HCV Protease HCV | ||
结构式
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