Procaine hydrochloride

CAS No.	51-05-8	Cat. No.	BCP28535
Name	Procaine hydrochloride
Synonyms	Procaine Hcl; Novocaine hydrochloride;
Formula	C13H21ClN2O2	M. Wt	272.77

Description	Procaine Hydrochloride is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine hydrochloride has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line, Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound.
Pathways	Ion Channel/Membrane Transporter
Targets	GABA Receptor

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