Fmoc-Val-Cit-PAB

  • Chemical Properties
CAS No. 159858-22-7 Cat. No. BCP13071
Name Fmoc-Val-Cit-PAB
Synonyms ADC linker;
Formula C33H39N5O6 M. Wt 601.69
  • Biological Activity
Description Fmoc-Val-Cit-PAB-OH is a useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC) for targeting drug delivery. The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.
Pathways Others Pathway 
Targets ADC Related 

Structure

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