SB-334867 hydrochloride
| CAS号 | 249889-64-3 | 货号 | BCP13166 |
| 中文名 | SB-334867 hydrochloride | ||
| 英文名 | SB-334867 hydrochloride | ||
| 中文别名 | |||
| 英文别名 | SB334867 hydrochloride;SB 334867 hydrochloride;SB334867 HCl;SB-334867 HCl;SB 334867 HCl; | ||
| 分子式 | C18H14N4O2.ClH | 分子量 | 354.79 |
| 生物活性 | SB334867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other physiological processes. Orexin antagonists have multiple potential clinical applications including the treatment of drug addiction, insomnia, obesity and diabetes. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | OX Receptor | ||
结构式
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