Fostemsavir
| CAS No. | 864953-29-7 | Cat. No. | BCP13226 |
| Name | Fostemsavir | ||
| Synonyms | BMS-663068;BMS663068; BMS 663068; | ||
| Formula | C25H26N7O8P | M. Wt | 583.49 |
| Description | BMS-663068 is a prodrug for BMS-626529 which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Administration of BMS-663068 for 8 days with or without ritonavir resulted in substantial declines in plasma HIV-1 RNA levels and was generally well tolerated. Longer-term clinical trials of BMS-663068 as part of combination antiretroviral therapy are warranted. | ||
| Pathways | Microbiology/Virology | ||
| Targets | HIV | ||
Structure
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