UNC 0224
CAS No. | 1197196-48-7 | Cat. No. | BCP13205 |
Name | UNC 0224 | ||
Synonyms | UNC-0224;UNC0224; | ||
Formula | C26H43N7O2 | M. Wt | 485.67 |
Description | UNC0224(Compound 8) also potently inhibited GLP with an IC50 of 20 nM and 58 nM in the Thioglo assay and and AlphaScreen, respectively. 8 was more than 1000-fold selective for G9a over SET7/9 (a H3K4 HMT) and SET8/PreSET7 (a H4K20 HMT) in Thioglo-based biochemical assays. | ||
Pathways | Epigenetics | ||
Targets | Histone Methyltransferase |
Structure
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