UNC 0224

  • Chemical Properties
CAS No. 1197196-48-7 Cat. No. BCP13205
Name UNC 0224
Synonyms UNC-0224;UNC0224;
Formula C26H43N7O2 M. Wt 485.67
  • Biological Activity
Description UNC0224(Compound 8) also potently inhibited GLP with an IC50 of 20 nM and 58 nM in the Thioglo assay and and AlphaScreen, respectively. 8 was more than 1000-fold selective for G9a over SET7/9 (a H3K4 HMT) and SET8/PreSET7 (a H4K20 HMT) in Thioglo-based biochemical assays.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

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