Afloqualone

  • Chemical Properties
CAS No. 56287-74-2 Cat. No. BCP13264
Name Afloqualone
Synonyms HQ-495; HQ495; HQ 495;
Formula C16H14FN3O M. Wt 283.3
  • Biological Activity
Description Afloqualone, also known as HQ-495, is a centrally acting muscle relaxant. Afloqualone inhibits vestibular nystagmus probably due to both inhibition of selective polysynaptic transmission and enhancement of the effects of GABA and glycine in the lateral vestibular nucleus (LVN), and its GABA-enhancing effect is thought to be attributable to the increased sensitivity of GABA receptors of the LVN neuron site.
Pathways Ion Channel/Membrane Transporter 
Targets GABA Receptor 

Structure

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