Lactacystin

  • Chemical Properties
CAS No. 133343-34-7 Cat. No. BCP13243
Name Lactacystin
Synonyms
Formula C15H24N2O7S M. Wt 376.43
  • Biological Activity
Description Lactacystin is a proteasome inhibitor found in Streptomyces. It increases the Bax/Bcl-2 ratio and inhibits proliferation of glioma cells, inhibits growth and migration of smooth muscle cells, and suppresses infiltration of neutrophils and decreases levels of ICAM-1 in liver injury models.
Pathways Protease/Metabolic Enzyme 
Targets Proteasome 

Structure

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