MK-5172
| CAS号 | 1350514-68-9 | 货号 | BCP28567 |
| 中文名 | MK-5172 | ||
| 英文名 | MK-5172 | ||
| 中文别名 | |||
| 英文别名 | MK 5172; MK5172; Grazoprevir; | ||
| 分子式 | C38H50N6O9S | 分子量 | 766.91 |
| 生物活性 | MK-5172, also known as Grazoprevir, is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, following promising results in Phase II when used in combination with the NS5A replication complex inhibitor elbasvir, either with or without ribavirin.Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets. It has good activity against a range of HCV genotype variants, including some that are resistant to most currently used antiviral medications. | ||
| 信号通路 | Protease/Metabolic Enzyme Microbiology/Virology | ||
| 靶 点 | HCV Protease HCV | ||
结构式
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