Rimegepant

  • Chemical Properties
CAS No. 1289023-67-1 Cat. No. BCP28575
Name Rimegepant
Synonyms BHV-3000; BHV 3000; BHV3000;BMS 927711; BMS927711; BMS-927711;
Formula C28H28F2N6O3 M. Wt 534.56
  • Biological Activity
Description Rimegepant, also known as BMS-927711, is a potent, selective, competitive and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine. Rimegepant has shown in vivo efficacy without vasoconstrictor effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets CGRP Receptor 

Structure

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