Nivolumab

  • Chemical Properties
CAS No. 946414-94-4 Cat. No. BCP28580
Name Nivolumab
Synonyms Opdivo; ONO-4538; BMS-936558; MDX1106;ONO 4538; BMS 936558; MDX 1106;ONO4538; BMS936558; MDX-1106;
Formula M. Wt
  • Biological Activity
Description Nivolumab, marketed as Opdivo, is a humanized IgG4 anti-PD-1 monoclonal antibody used to treat cancer. Nivolumab works as a checkpoint inhibitor, blocking a signal that would have prevented activated T cells from attacking the cancer, thus allowing the immune system to clear the cancer.
Pathways Apoptosis Pathway 
Targets PD 1/PD L1 

Structure

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