Gatifloxacin
| CAS No. | 112811-59-3 | Cat. No. | BCP13408 |
| Name | Gatifloxacin | ||
| Synonyms | AM 1155; BMS 206584-01; PD 135432;AM1155;BMS206584-01;PD135432;AM-1155;PD-135432; | ||
| Formula | C19H22FN3O4 | M. Wt | 375.39 |
| Description | Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Gatifloxacin had activity equal to that of tosufloxacin and activity more potent than those of norfloxacin, ofloxacin, ciprofloxacin, and sparfloxacin against the second-step mutants (grlA gyrA; gatifloxacin MIC range, 1.56 to 3.13 microg/ml) and had the most potent activity against the third-step mutants (grlA gyrA grlA; gatifloxacin MIC range, 1.56 to 6.25 microg/ml), suggesting that gatifloxacin possesses the most potent inhibitory activity against singly mutated topo IV and singly mutated DNA gyrase among the quinolones tested. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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